Upload A document to a Document Library through programmatically...

Note: I used Visual Webpart which template in visual studio for sharepoint.

protected void btnUpload_Click(object sender, EventArgs e)

        {

            BindDataInSPList();

        }

        private void BindDataInSPList()

        {

            try

            {

                SPSite oSite = SPContext.Current.Site;

                SPWeb oWeb = oSite.OpenWeb();

                oWeb.AllowUnsafeUpdates = true;

                SPDocumentLibrary mylist = oWeb.Lists["CV"] as SPDocumentLibrary;

                string fileName = System.IO.Path.GetFileName(FileUpLoadDoc.PostedFile.FileName);

                //Get file extension ( *.doc OR *.docx )

                string fileExtension = FileUpLoadDoc.FileName.Substring(FileUpLoadDoc.FileName.IndexOf("."));

                byte[] fileBytes = FileUpLoadDoc.FileBytes;

                string destUrl = mylist.RootFolder.Url + "/" + fileName;

                SPFile destFile = mylist.RootFolder.Files.Add(destUrl, fileBytes, true);

                destFile.Update();

                oWeb.AllowUnsafeUpdates = true;

                //update metadata

                destFile.Item["Name"] = txtSTDFNNAme.Text;

                //destFile.Item["Address"] = txtAddress.Text;

                destFile.Item.Update();

            }

            catch (Exception ex)

            { ; }

        }